About Tumor protein D54
Tumor protein D54 (TPD52L2) is a protein
from Homo sapiens identified by UniProt accession
O43399, 206 residues long.
MolForge cross-references it against 0 known binders and
66 disease associations.
Target properties
| Protein name | Tumor protein D54 |
|---|
| UniProt accession | O43399 |
|---|
| Gene | TPD52L2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (66)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.12
- hematocrit · score 0.11
- hemoglobin measurement · score 0.09
- cardiovascular disease · score 0.09
- red blood cell density measurement · score 0.08
- neoplasm · score 0.08
- nonpapillary renal cell carcinoma · score 0.07
- gastric carcinoma · score 0.07
- systolic blood pressure · score 0.07
- lung adenocarcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43399-F1 | alphafold | PREDICTED | 68.61 | — |
Amino-acid sequence (206 residues)
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR AELTKVEEEI VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSSAYVKTS EKLGEWNEKV TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA ISRKLGDMRN SATFKSFEDR VGTIKSKVVG DRENGSDNLP SSAGSGDKPL SDPAPF
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