Ragulator complex protein LAMTOR5 (LAMTOR5)

About Ragulator complex protein LAMTOR5

Ragulator complex protein LAMTOR5 (LAMTOR5) is a protein from Homo sapiens identified by UniProt accession O43504, 91 residues long. MolForge cross-references it against 0 known binders and 86 disease associations.

Target properties

Protein name	Ragulator complex protein LAMTOR5
UniProt accession	O43504
Gene	LAMTOR5
Organism	Homo sapiens
Length	91 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (86)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.54
lysosomal storage disease · score 0.33
breast adenocarcinoma · score 0.28
thyroid gland adenocarcinoma · score 0.28
endometrial cancer · score 0.23
squamous cell lung carcinoma · score 0.19
ovarian cancer · score 0.18
multiple myeloma · score 0.17
gastric adenocarcinoma · score 0.14
clear cell renal carcinoma · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43504-F1	alphafold	PREDICTED	96.56	—

Amino-acid sequence (91 residues)

MEATLEQHLE DTMKNPSIVG VLCTDSQGLN LGCRGTLSDE HAGVISVLAQ QAAKLTSDPT DIPVVCLESD NGNIMIQKHD GITVAVHKMA S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards