About Carbohydrate sulfotransferase 10
Carbohydrate sulfotransferase 10 (CHST10) is a protein
from Homo sapiens identified by UniProt accession
O43529, 356 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Carbohydrate sulfotransferase 10 |
|---|
| UniProt accession | O43529 |
|---|
| Gene | CHST10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 356 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- psoriasis · score 0.26
- smoking initiation · score 0.12
- mathematical ability · score 0.09
- diet measurement · score 0.08
- 46,XX gonadal dysgenesis · score 0.07
- primary ovarian insufficiency · score 0.07
- Testicular regression syndrome · score 0.06
- Abnormal urine sodium concentration · score 0.06
- Perrault syndrome · score 0.06
- self reported educational attainment · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43529-F1 | alphafold | PREDICTED | 86.09 | — |
Amino-acid sequence (356 residues)
MHHQWLLLAA CFWVIFMFMV ASKFITLTFK DPDVYSAKQE FLFLTTMPEV RKLPEEKHIP EELKPTGKEL PDSQLVQPLV YMERLELIRN VCRDDALKNL SHTPVSKFVL DRIFVCDKHK ILFCQTPKVG NTQWKKVLIV LNGAFSSIEE IPENVVHDHE KNGLPRLSSF SDAEIQKRLK TYFKFFIVRD PFERLISAFK DKFVHNPRFE PWYRHEIAPG IIRKYRRNRT ETRGIQFEDF VRYLGDPNHR WLDLQFGDHI IHWVTYVELC APCEIMYSVI GHHETLEDDA PYILKEAGID HLVSYPTIPP GITVYNRTKV EHYFLGISKR DIRRLYARFE GDFKLFGYQK PDFLLN
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