About Charged multivesicular body protein 2a
Charged multivesicular body protein 2a (CHMP2A) is a protein
from Homo sapiens identified by UniProt accession
O43633, 222 residues long.
MolForge cross-references it against 0 known binders and
61 disease associations.
Target properties
| Protein name | Charged multivesicular body protein 2a |
|---|
| UniProt accession | O43633 |
|---|
| Gene | CHMP2A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 222 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (61)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- HIV infection · score 0.46
- viral disease · score 0.46
- severe acute respiratory syndrome · score 0.37
- COVID-19 · score 0.37
- neoplasm · score 0.07
- colorectal adenoma · score 0.07
- colorectal cancer · score 0.07
- head and neck squamous cell carcinoma · score 0.06
- lung adenocarcinoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43633-F1 | alphafold | PREDICTED | 75.19 | — |
Amino-acid sequence (222 residues)
MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS NLPSTGGSLS VAAGGKKAEA AASALADADA DLEERLKNLR RD
Explore Charged multivesicular body protein 2a with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets