Forkhead box protein S1 (FOXS1)

About Forkhead box protein S1

Forkhead box protein S1 (FOXS1) is a protein from Homo sapiens identified by UniProt accession O43638, 330 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Forkhead box protein S1
UniProt accession	O43638
Gene	FOXS1
Organism	Homo sapiens
Length	330 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.25
mean corpuscular hemoglobin · score 0.24
mean corpuscular hemoglobin concentration · score 0.23
neurodegenerative disease · score 0.23
reticulocyte measurement · score 0.12
neoplasm · score 0.10
hepatocellular carcinoma · score 0.10
Immature Reticulocyte Fraction Measurement · score 0.09
cancer · score 0.09
body height · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43638-F1	alphafold	PREDICTED	63.01	—

Amino-acid sequence (330 residues)

MQQQPLPGPG APTTEPTKPP YSYIALIAMA IQSSPGQRAT LSGIYRYIMG RFAFYRHNRP GWQNSIRHNL SLNECFVKVP RDDRKPGKGS YWTLDPDCHD MFEHGSFLRR RRRFTRQTGA EGTRGPAKAR RGPLRATSQD PGVPNATTGR QCSFPPELPD PKGLSFGGLV GAMPASMCPA TTDGRPRPPM EPKEISTPKP ACPGELPVAT SSSSCPAFGF PAGFSEAESF NKAPTPVLSP ESGIGSSYQC RLQALNFCMG ADPGLEHLLA SAAPSPAPPT PPGSLRAPLP LPTDHKEPWV AGGFPVQGGS GYPLGLTPCL YRTPGMFFFE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards