About Regulator of G-protein signaling 10
Regulator of G-protein signaling 10 (RGS10) is a protein
from Homo sapiens identified by UniProt accession
O43665, 181 residues long.
MolForge cross-references it against 0 known binders and
134 disease associations.
Target properties
| Protein name | Regulator of G-protein signaling 10 |
|---|
| UniProt accession | O43665 |
|---|
| Gene | RGS10 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 181 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (134)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.21
- myeloid white cell count · score 0.20
- risky sexual behaviour measurement · score 0.11
- MODY · score 0.10
- stressful life event measurement · score 0.10
- depressive symptom measurement · score 0.10
- type 2 diabetes mellitus · score 0.10
- appendicular lean mass · score 0.09
- lean body mass · score 0.09
- fat body mass · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43665-F1 | alphafold | PREDICTED | 81.38 | — |
Amino-acid sequence (181 residues)
MFNRAVSRLS RKRPPSDIHD SDGSSSSSHQ SLKSTAKWAA SLENLLEDPE GVKRFREFLK KEFSEENVLF WLACEDFKKM QDKTQMQEKA KEIYMTFLSS KASSQVNVEG QSRLNEKILE EPHPLMFQKL QDQIFNLMKY DSYSRFLKSD LFLKHKRTEE EEEDLPDAQT AAKRASRIYN T
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