A-kinase anchor protein 7 isoforms alpha and beta (AKAP7)

Homo sapiens — UniProt O43687

Gene: AKAP7Homo sapiensSwissProt reviewed

About A-kinase anchor protein 7 isoforms alpha and beta

A-kinase anchor protein 7 isoforms alpha and beta (AKAP7) is a protein from Homo sapiens identified by UniProt accession O43687, 104 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

Target properties

Protein nameA-kinase anchor protein 7 isoforms alpha and beta
UniProt accessionO43687
GeneAKAP7
OrganismHomo sapiens
Length104 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (68)

Diseases linked to this target (Open Targets).

  • adolescent idiopathic scoliosis · score 0.33
  • BMI-adjusted hip circumference · score 0.29
  • body weight · score 0.29
  • metabolite measurement · score 0.25
  • neurodegenerative disease · score 0.20
  • lean body mass · score 0.19
  • Stroke · score 0.07
  • vital capacity · score 0.07
  • body height · score 0.07
  • Osteoporosis · score 0.06

3D Structure

Predicted structure for O43687 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (104 residues)

MGQLCCFPFS RDEGKISELE SSSSAVLQRY SKDIPSWSSG EKNGGEPDDA ELVRLSKRLV ENAVLKAVQQ YLEETQNKNK PGEGSSVKTE AADQNGNDNE NNRK

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Quick facts

UniProtO43687
GeneAKAP7
OrganismHomo sapiens
Length104
Binders0
Diseases68
View on UniProt