About Peptidase inhibitor 15
Peptidase inhibitor 15 (PI15) is a protein
from Homo sapiens identified by UniProt accession
O43692, 258 residues long.
MolForge cross-references it against 0 known binders and
57 disease associations.
Target properties
| Protein name | Peptidase inhibitor 15 |
|---|
| UniProt accession | O43692 |
|---|
| Gene | PI15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (57)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.41
- aortic measurement · score 0.34
- adolescent idiopathic scoliosis · score 0.28
- Abnormality of refraction · score 0.28
- forced expiratory volume · score 0.11
- neoplasm · score 0.08
- cholangiocarcinoma · score 0.08
- hepatocellular carcinoma · score 0.08
- breast carcinoma · score 0.06
- sitting height measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43692-F1 | alphafold | PREDICTED | 83.14 | — |
Amino-acid sequence (258 residues)
MIAISAVSSA LLFSLLCEAS TVVLLNSTDS SPPTNNFTDI EAALKAQLDS ADIPKARRKR YISQNDMIAI LDYHNQVRGK VFPPAANMEY MVWDENLAKS AEAWAATCIW DHGPSYLLRF LGQNLSVRTG RYRSILQLVK PWYDEVKDYA FPYPQDCNPR CPMRCFGPMC THYTQMVWAT SNRIGCAIHT CQNMNVWGSV WRRAVYLVCN YAPKGNWIGE APYKVGVPCS SCPPSYGGSC TDNLCFPGVT SNYLYWFK
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