About Calcineurin B homologous protein 2
Calcineurin B homologous protein 2 (CHP2) is a protein
from Homo sapiens identified by UniProt accession
O43745, 196 residues long.
MolForge cross-references it against 0 known binders and
59 disease associations.
Target properties
| Protein name | Calcineurin B homologous protein 2 |
|---|
| UniProt accession | O43745 |
|---|
| Gene | CHP2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (59)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.36
- Mycobacterium avium complex disease · score 0.25
- eosinophil percentage of leukocytes · score 0.10
- body mass index · score 0.09
- non-small cell lung carcinoma · score 0.08
- Barrett's esophagus · score 0.07
- esophageal adenocarcinoma · score 0.03
- neoplasm · score 0.03
- exercise-induced hyperinsulinism · score 0.03
- ulcerative colitis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43745-F1 | alphafold | PREDICTED | 86.51 | — |
Amino-acid sequence (196 residues)
MGSRSSHAAV IPDGDSIRRE TGFSQASLLR LHHRFRALDR NKKGYLSRMD LQQIGALAVN PLGDRIIESF FPDGSQRVDF PGFVRVLAHF RPVEDEDTET QDPKKPEPLN SRRNKLHYAF QLYDLDRDGK ISRHEMLQVL RLMVGVQVTE EQLENIADRT VQEADEDGDG AVSFVEFTKS LEKMDVEQKM SIRILK
Explore Calcineurin B homologous protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets