Olfactory receptor 1F1 (OR1F1)

About Olfactory receptor 1F1

Olfactory receptor 1F1 (OR1F1) is a protein from Homo sapiens identified by UniProt accession O43749, 312 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Olfactory receptor 1F1
UniProt accession	O43749
Gene	OR1F1
Organism	Homo sapiens
Length	312 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

clear cell renal carcinoma · score 0.18
breast adenocarcinoma · score 0.18
mean corpuscular volume · score 0.13
gut microbiome measurement · score 0.11
vital capacity · score 0.04
breast cancer · score 0.01
attention deficit hyperactivity disorder · score 0.00
nervous system disease · score 0.00
Parkinson disease · score 0.00
Mayer-Rokitansky-Kuster-Hauser syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43749-F1	alphafold	PREDICTED	85.87	—

Amino-acid sequence (312 residues)

MSGTNQSSVS EFLLLGLSRQ PQQQHLLFVF FLSMYLATVL GNLLIILSVS IDSCLHTPMY FFLSNLSFVD ICFSFTTVPK MLANHILETQ TISFCGCLTQ MYFVFMFVDM DNFLLAVMAY DHFVAVCHPL HYTAKMTHQL CALLVAGLWV VANLNVLLHT LLMAPLSFCA DNAITHFFCD VTPLLKLSCS DTHLNEVIIL SEGALVMITP FLCILASYMH ITCTVLKVPS TKGRWKAFST CGSHLAVVLL FYSTIIAVYF NPLSSHSAEK DTMATVLYTV VTPMLNPFIY SLRNRYLKGA LKKVVGRVVF SV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards