Alpha-endosulfine (ENSA)

About Alpha-endosulfine

Alpha-endosulfine (ENSA) is a protein from Homo sapiens identified by UniProt accession O43768, 121 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.

Target properties

Protein name	Alpha-endosulfine
UniProt accession	O43768
Gene	ENSA
Organism	Homo sapiens
Length	121 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (69)

Diseases linked to this target (Open Targets).

monocyte count · score 0.31
eosinophil count · score 0.30
monocyte percentage of leukocytes · score 0.26
eosinophil percentage of leukocytes · score 0.26
basophil count · score 0.23
leukocyte count · score 0.20
forced expiratory volume · score 0.20
vital capacity · score 0.20
granulocyte percentage of myeloid white cells · score 0.19
sum of eosinophil and basophil counts · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43768-F1	alphafold	PREDICTED	67.39	—

Amino-acid sequence (121 residues)

MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards