Peroxisomal membrane protein PMP34 (SLC25A17)

About Peroxisomal membrane protein PMP34

Peroxisomal membrane protein PMP34 (SLC25A17) is a protein from Homo sapiens identified by UniProt accession O43808, 307 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.

Target properties

Protein name	Peroxisomal membrane protein PMP34
UniProt accession	O43808
Gene	SLC25A17
Organism	Homo sapiens
Length	307 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (89)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
low density lipoprotein cholesterol measurement · score 0.23
calcium measurement · score 0.19
bipolar disorder · score 0.09
C-reactive protein measurement · score 0.09
vitamin D measurement · score 0.08
head and neck squamous cell carcinoma · score 0.08
triple-negative breast cancer · score 0.07
mathematical ability · score 0.07
apolipoprotein B measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43808-F1	alphafold	PREDICTED	85.40	—

Amino-acid sequence (307 residues)

MASVLSYESL VHAVAGAVGS VTAMTVFFPL DTARLRLQVD EKRKSKTTHM VLLEIIKEEG LLAPYRGWFP VISSLCCSNF VYFYTFNSLK ALWVKGQHST TGKDLVVGFV AGVVNVLLTT PLWVVNTRLK LQGAKFRNED IVPTNYKGII DAFHQIIRDE GISALWNGTF PSLLLVFNPA IQFMFYEGLK RQLLKKRMKL SSLDVFIIGA VAKAIATTVT YPLQTVQSIL RFGRHRLNPE NRTLGSLRNI LYLLHQRVRR FGIMGLYKGL EAKLLQTVLT AALMFLVYEK LTAATFTVMG LKRAHQH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards