Glutathione S-transferase LANCL1 (LANCL1)

About Glutathione S-transferase LANCL1

Glutathione S-transferase LANCL1 (LANCL1) is a protein from Homo sapiens identified by UniProt accession O43813, 399 residues long. MolForge cross-references it against 0 known binders and 199 disease associations.

Target properties

Protein name	Glutathione S-transferase LANCL1
UniProt accession	O43813
Gene	LANCL1
Organism	Homo sapiens
Length	399 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (199)

Diseases linked to this target (Open Targets).

sex hormone-binding globulin measurement · score 0.35
erythrocyte count · score 0.33
hemoglobin measurement · score 0.29
creatinine measurement · score 0.28
body height · score 0.27
glycine measurement · score 0.22
amino acid measurement · score 0.19
Headache · score 0.18
cortical surface area measurement · score 0.13
alcohol drinking · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43813-F1	alphafold	PREDICTED	97.51	—

Amino-acid sequence (399 residues)

MAQRAFPNPY ADYNKSLAEG YFDAAGRLTP EFSQRLTNKI RELLQQMERG LKSADPRDGT GYTGWAGIAV LYLHLYDVFG DPAYLQLAHG YVKQSLNCLT KRSITFLCGD AGPLAVAAVL YHKMNNEKQA EDCITRLIHL NKIDPHAPNE MLYGRIGYIY ALLFVNKNFG VEKIPQSHIQ QICETILTSG ENLARKRNFT AKSPLMYEWY QEYYVGAAHG LAGIYYYLMQ PSLQVSQGKL HSLVKPSVDY VCQLKFPSGN YPPCIGDNRD LLVHWCHGAP GVIYMLIQAY KVFREEKYLC DAYQCADVIW QYGLLKKGYG LCHGSAGNAY AFLTLYNLTQ DMKYLYRACK FAEWCLEYGE HGCRTPDTPF SLFEGMAGTI YFLADLLVPT KARFPAFEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards