About Angiopoietin-related protein 7
Angiopoietin-related protein 7 (ANGPTL7) is a protein
from Homo sapiens identified by UniProt accession
O43827, 346 residues long.
MolForge cross-references it against 0 known binders and
90 disease associations.
Target properties
| Protein name | Angiopoietin-related protein 7 |
|---|
| UniProt accession | O43827 |
|---|
| Gene | ANGPTL7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 346 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (90)
Diseases linked to this target (Open Targets).
- intraocular pressure measurement · score 0.56
- eye measurement · score 0.55
- corneal resistance factor · score 0.29
- refractive error measurement · score 0.25
- glaucoma · score 0.22
- corneal topography · score 0.19
- body mass index · score 0.16
- lean body mass · score 0.16
- open-angle glaucoma · score 0.14
- sex hormone-binding globulin measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43827-F1 | alphafold | PREDICTED | 86.01 | — |
Amino-acid sequence (346 residues)
MLKKPLSAVT WLCIFIVAFV SHPAWLQKLS KHKTPAQPQL KAANCCEEVK ELKAQVANLS SLLSELNKKQ ERDWVSVVMQ VMELESNSKR MESRLTDAES KYSEMNNQID IMQLQAAQTV TQTSADAIYD CSSLYQKNYR ISGVYKLPPD DFLGSPELEV FCDMETSGGG WTIIQRRKSG LVSFYRDWKQ YKQGFGSIRG DFWLGNEHIH RLSRQPTRLR VEMEDWEGNL RYAEYSHFVL GNELNSYRLF LGNYTGNVGN DALQYHNNTA FSTKDKDNDN CLDKCAQLRK GGYWYNCCTD SNLNGVYYRL GEHNKHLDGI TWYGWHGSTY SLKRVEMKIR PEDFKP
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