About Calumenin
Calumenin (CALU) is a protein
from Homo sapiens identified by UniProt accession
O43852, 315 residues long.
MolForge cross-references it against 0 known binders and
95 disease associations.
Target properties
| Protein name | Calumenin |
|---|
| UniProt accession | O43852 |
|---|
| Gene | CALU |
|---|
| Organism | Homo sapiens |
|---|
| Length | 315 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (95)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.39
- mathematical ability · score 0.36
- cognitive function measurement · score 0.34
- intelligence · score 0.31
- neurodegenerative disease · score 0.31
- Alzheimer disease · score 0.31
- Parkinson disease · score 0.31
- lysosomal storage disease · score 0.31
- multiple sclerosis · score 0.31
- breast adenocarcinoma · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43852-F1 | alphafold | PREDICTED | 79.48 | — |
Amino-acid sequence (315 residues)
MDLRQFLMCL SLCTAFALSK PTEKKDRVHH EPQLSDKVHN DAQSFDYDHD AFLGAEEAKT FDQLTPEESK ERLGKIVSKI DGDKDGFVTV DELKDWIKFA QKRWIYEDVE RQWKGHDLNE DGLVSWEEYK NATYGYVLDD PDPDDGFNYK QMMVRDERRF KMADKDGDLI ATKEEFTAFL HPEEYDYMKD IVVQETMEDI DKNADGFIDL EEYIGDMYSH DGNTDEPEWV KTEREQFVEF RDKNRDGKMD KEETKDWILP SDYDHAEAEA RHLVYESDQN KDGKLTKEEI VDKYDLFVGS QATDFGEALV RHDEF
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