About EGF-like repeat and discoidin I-like domain-containing protein 3
EGF-like repeat and discoidin I-like domain-containing protein 3 (EDIL3) is a protein
from Homo sapiens identified by UniProt accession
O43854, 480 residues long.
MolForge cross-references it against 0 known binders and
181 disease associations.
Target properties
| Protein name | EGF-like repeat and discoidin I-like domain-containing protein 3 |
|---|
| UniProt accession | O43854 |
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| Gene | EDIL3 |
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| Organism | Homo sapiens |
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| Length | 480 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (181)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.27
- metabolite measurement · score 0.26
- neoplasm · score 0.11
- cancer · score 0.09
- psoriasis · score 0.09
- hepatocellular carcinoma · score 0.09
- chronic obstructive pulmonary disease · score 0.09
- Sepsis · score 0.09
- gonorrhea · score 0.08
- experimental autoimmune encephalomyelitis · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O43854-F1 | alphafold | PREDICTED | 87.62 | — |
Amino-acid sequence (480 residues)
MKRSVAVWLL VGLSLGVPQF GKGDICDPNP CENGGICLPG LADGSFSCEC PDGFTDPNCS SVVEVASDEE EPTSAGPCTP NPCHNGGTCE ISEAYRGDTF IGYVCKCPRG FNGIHCQHNI NECEVEPCKN GGICTDLVAN YSCECPGEFM GRNCQYKCSG PLGIEGGIIS NQQITASSTH RALFGLQKWY PYYARLNKKG LINAWTAAEN DRWPWIQINL QRKMRVTGVI TQGAKRIGSP EYIKSYKIAY SNDGKTWAMY KVKGTNEDMV FRGNIDNNTP YANSFTPPIK AQYVRLYPQV CRRHCTLRME LLGCELSGCS EPLGMKSGHI QDYQITASSI FRTLNMDMFT WEPRKARLDK QGKVNAWTSG HNDQSQWLQV DLLVPTKVTG IITQGAKDFG HVQFVGSYKL AYSNDGEHWT VYQDEKQRKD KVFQGNFDND THRKNVIDPP IYARHIRILP WSWYGRITLR SELLGCTEEE
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