C-X-C motif chemokine 13 (CXCL13)

About C-X-C motif chemokine 13

C-X-C motif chemokine 13 (CXCL13) is a protein from Homo sapiens identified by UniProt accession O43927, 109 residues long. MolForge cross-references it against 0 known binders and 696 disease associations.

Target properties

Protein name	C-X-C motif chemokine 13
UniProt accession	O43927
Gene	CXCL13
Organism	Homo sapiens
Length	109 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (696)

Diseases linked to this target (Open Targets).

tonsillectomy risk measurement · score 0.41
neurodegenerative disease · score 0.39
neurofibrillary tangles measurement · score 0.35
ovarian cancer · score 0.26
drug use measurement · score 0.20
thyroid gland adenocarcinoma · score 0.16
neoplasm · score 0.12
neurosyphilis · score 0.11
Rheumatoid arthritis · score 0.11
non-Hodgkins lymphoma · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O43927-F1	alphafold	PREDICTED	83.86	—

Amino-acid sequence (109 residues)

MKFISTSLLL MLLVSSLSPV QGVLEVYYTS LRCRCVQESS VFIPRRFIDR IQILPRGNGC PRKEIIVWKK NKSIVCVDPQ AEWIQRMMEV LRKRSSSTLP VPVFKRKIP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards