About Protein ZNRD2
Protein ZNRD2 (ZNRD2) is a protein
from Homo sapiens identified by UniProt accession
O60232, 199 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Protein ZNRD2 |
|---|
| UniProt accession | O60232 |
|---|
| Gene | ZNRD2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.16
- type 2 diabetes mellitus · score 0.15
- heel bone mineral density · score 0.14
- alkaline phosphatase measurement · score 0.13
- osteoarthritis · score 0.12
- total hip arthroplasty · score 0.12
- osteoarthritis, hip · score 0.11
- refractive error measurement · score 0.11
- Drugs used in diabetes use measurement · score 0.11
- otosclerosis · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60232-F1 | alphafold | PREDICTED | 77.60 | — |
Amino-acid sequence (199 residues)
MALNGAEVDD FSWEPPTEAE TKVLQARRER QDRISRLMGD YLLRGYRMLG ETCADCGTIL LQDKQRKIYC VACQELDSDV DKDNPALNAQ AALSQAREHQ LASASELPLG SRPAPQPPVP RPEHCEGAAA GLKAAQGPPA PAVPPNTDVM ACTQTALLQK LTWASAELGS STSLETSIQL CGLIRACAEA LRSLQQLQH
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