About Fibroblast growth factor 17
Fibroblast growth factor 17 (FGF17) is a protein
from Homo sapiens identified by UniProt accession
O60258, 216 residues long.
MolForge cross-references it against 0 known binders and
65 disease associations.
Target properties
| Protein name | Fibroblast growth factor 17 |
|---|
| UniProt accession | O60258 |
|---|
| Gene | FGF17 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 216 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (65)
Diseases linked to this target (Open Targets).
- cancer · score 0.60
- bone development disease · score 0.60
- Kallmann syndrome · score 0.55
- acrocephalosyndactyly · score 0.37
- ovarian carcinoma · score 0.37
- craniosynostosis · score 0.37
- hypogonadotropic hypogonadism · score 0.37
- female reproductive endometrioid cancer · score 0.37
- endometrial cancer · score 0.30
- cutaneous melanoma · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60258-F1 | alphafold | PREDICTED | 86.16 | — |
Amino-acid sequence (216 residues)
MGAARLLPNL TLCLQLLILC CQTQGENHPS PNFNQYVRDQ GAMTDQLSRR QIREYQLYSR TSGKHVQVTG RRISATAEDG NKFAKLIVET DTFGSRVRIK GAESEKYICM NKRGKLIGKP SGKSKDCVFT EIVLENNYTA FQNARHEGWF MAFTRQGRPR QASRSRQNQR EAHFIKRLYQ GQLPFPNHAE KQKQFEFVGS APTRRTKRTR RPQPLT
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