Guanine nucleotide-binding protein G(I)/G(S)/G(O)…

About Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7) is a protein from Homo sapiens identified by UniProt accession O60262, 68 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.

Target properties

Protein name	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
UniProt accession	O60262
Gene	GNG7
Organism	Homo sapiens
Length	68 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (117)

Diseases linked to this target (Open Targets).

hypertension · score 0.43
essential hypertension · score 0.31
hemoglobin measurement · score 0.30
high density lipoprotein cholesterol measurement · score 0.30
C-reactive protein measurement · score 0.30
heel bone mineral density · score 0.27
chronotype measurement · score 0.27
type 2 diabetes mellitus · score 0.27
diabetic nephropathy · score 0.27
erythrocyte count · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60262-F1	alphafold	PREDICTED	90.87	—

Amino-acid sequence (68 residues)

MSATNNIAQA RKLVEQLRIE AGIERIKVSK AASDLMSYCE QHARNDPLLV GVPASENPFK DKKPCIIL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7)