About Zinc finger protein 862
Zinc finger protein 862 (ZNF862) is a protein
from Homo sapiens identified by UniProt accession
O60290, 1169 residues long.
MolForge cross-references it against 0 known binders and
4 disease associations.
Target properties
| Protein name | Zinc finger protein 862 |
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| UniProt accession | O60290 |
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| Gene | ZNF862 |
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| Organism | Homo sapiens |
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| Length | 1169 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (4)
Diseases linked to this target (Open Targets).
- hereditary gingival fibromatosis · score 0.27
- drug use measurement · score 0.15
- adolescent idiopathic scoliosis · score 0.09
- systemic juvenile idiopathic arthritis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60290-F1 | alphafold | PREDICTED | 66.38 | — |
Amino-acid sequence (1169 residues)
MEPRESGKAP VTFDDITVYL LQEEWVLLSQ QQKELCGSNK LVAPLGPTVA NPELFRKFGR GPEPWLGSVQ GQRSLLEHHP GKKQMGYMGE MEVQGPTRES GQSLPPQKKA YLSHLSTGSG HIEGDWAGRN RKLLKPRSIQ KSWFVQFPWL IMNEEQTALF CSACREYPSI RDKRSRLIEG YTGPFKVETL KYHAKSKAHM FCVNALAARD PIWAARFRSI RDPPGDVLAS PEPLFTADCP IFYPPGPLGG FDSMAELLPS SRAELEDPGG DGAIPAMYLD CISDLRQKEI TDGIHSSSDI NILYNDAVES CIQDPSAEGL SEEVPVVFEE LPVVFEDVAV YFTREEWGML DKRQKELYRD VMRMNYELLA SLGPAAAKPD LISKLERRAA PWIKDPNGPK WGKGRPPGNK KMVAVREADT QASAADSALL PGSPVEARAS CCSSSICEEG DGPRRIKRTY RPRSIQRSWF GQFPWLVIDP KETKLFCSAC IERPNLHDKS SRLVRGYTGP FKVETLKYHE VSKAHRLCVN TVEIKEDTPH TALVPEISSD LMANMEHFFN AAYSIAYHSR PLNDFEKILQ LLQSTGTVIL GKYRNRTACT QFIKYISETL KREILEDVRN SPCVSVLLDS STDASEQACV GIYIRYFKQM EVKESYITLA PLYSETADGY FETIVSALDE LDIPFRKPGW VVGLGTDGSA MLSCRGGLVE KFQEVIPQLL PVHCVAHRLH LAVVDACGSI DLVKKCDRHI RTVFKFYQSS NKRLNELQEG AAPLEQEIIR LKDLNAVRWV ASRRRTLHAL LVSWPALARH LQRVAEAGGQ IGHRAKGMLK LMRGFHFVKF CHFLLDFLSI YRPLSEVCQK EIVLITEVNA TLGRAYVALE SLRHQAGPKE EEFNASFKDG RLHGICLDKL EVAEQRFQAD RERTVLTGIE YLQQRFDADR PPQLKNMEVF DTMAWPSGIE LASFGNDDIL NLARYFECSL PTGYSEEALL EEWLGLKTIA QHLPFSMLCK NALAQHCRFP LLSKLMAVVV CVPISTSCCE RGFKAMNRIR TDERTKLSNE VLNMLMMTAV NGVAVTEYDP QPAIQHWYLT SSGRRFSHVY TCAQVPARSP ASARLRKEEM GALYVEEPRT QKPPILPSRE AAEVLKDCIM EPPERLLYPH TSQEAPGMS
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