About Zinc finger C3H1 domain-containing protein
Zinc finger C3H1 domain-containing protein (ZFC3H1) is a protein
from Homo sapiens identified by UniProt accession
O60293, 1989 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Zinc finger C3H1 domain-containing protein |
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| UniProt accession | O60293 |
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| Gene | ZFC3H1 |
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| Organism | Homo sapiens |
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| Length | 1989 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60293-F1 | alphafold | PREDICTED | 57.99 | — |
Amino-acid sequence (1989 residues)
MATADTPAPA SSGLSPKEEG ELEDGEISDD DNNSQIRSRS SSSSSGGGLL PYPRRRPPHS ARGGGSGGGG GSSSSSSSSQ QQLRNFSRSR HASERGHLRG PSSYRPKEPF RSHPPSVRMP SSSLSESSPR PSFWERSHLA LDRFRFRGRP YRGGSRWSRG RGVGERGGKP GCRPPLGGGA GSGFSSSQSW REPSPPRKSS KSFGRSPSRK QNYSSKNENC VEETFEDLLL KYKQIQLELE CINKDEKLAL SSKEENVQED PKTLNFEDQT STDNVSITKD SSKEVAPEEK TQVKTFQAFE LKPLRQKLTL PGDKNRLKKV KDGAKPLSLK SDTTDSSQGL QDKEQNLTRR ISTSDILSEK KLGEDEEELS ELQLRLLALQ SASKKWQQKE QQVMKESKEK LTKTKTVQQK VKTSTKTHSA KKVSTTAKQA LRKQQTKAWK KLQQQKEQER QKEEDQRKQA EEEERRKREE EIRKIRDLSN QEEQYNRFMK LVGGKRRSRS KSSDPDLRRS LDKQPTDSGG GIYQYDNYEE VAMDTDSETS SPAPSPVQPP FFSECSLGYF SPAPSLSLPP PPQVSSLPPL SQPYVEGLCV SLEPLPPLPP LPPLPPEDPE QPPKPPFADE EEEEEMLLRE ELLKSLANKR AFKPEETSSN SDPPSPPVLN NSHPVPRSNL SIVSINTVSQ PRIQNPKFHR GPRLPRTVIS LPKHKSVVVT LNDSDDSESD GEASKSTNSV FGGLESMIKE ARRTAEQASK PKVPPKSEKE NDPLRTPEAL PEEKKIEYRL LKEEIANREK QRLIKSDQLK TSSSSPANSD VEIDGIGRIA MVTKQVTDAE SKLKKHRILL MKDESVLKNL VQQEAKKKES VRNAEAKITK LTEQLQATEK ILNVNRMFLK KLQEQIHRVQ QRVTIKKALT LKYGEELARA KAVASKEIGK RKLEQDRFGP NKMMRLDSSP VSSPRKHSAE LIAMEKRRLQ KLEYEYALKI QKLKEARALK AKEQQNISPV VEEEPEFSLP QPSLHDLTQD KLTLDTEEND VDDEILSGSS RERRRSFLES NYFTKPNLKH TDTANKECIN KLNKNTVEKP ELFLGLKIGE LQKLYSKADS LKQLILKTTT GITEKVLHGQ EISVDVDFVT AQSKTMEVKP CPFRPYHSPL LVFKSYRFSP YYRTKEKLPL SSVSYSNMIE PDQCFCRFDL TGTCNDDDCQ WQHIQDYTLS RKQLFQDILS YNLSLIGCAE TSTNEEITAS AEKYVEKLFG VNKDRMSMDQ MAVLLVSNIN ESKGHTPPFT TYKDKRKWKP KFWRKPISDN SFSSDEEQST GPIKYAFQPE NQINVPALDT VVTPDDVRYF TNETDDIANL EASVLENPSH VQLWLKLAYK YLNQNEGECS ESLDSALNVL ARALENNKDN PEIWCHYLRL FSKRGTKDEV QEMCETAVEY APDYQSFWTF LHLESTFEEK DYVCERMLEF LMGAAKQETS NILSFQLLEA LLFRVQLHIF TGRCQSALAI LQNALKSAND GIVAEYLKTS DRCLAWLAYI HLIEFNILPS KFYDPSNDNP SRIVNTESFV MPWQAVQDVK TNPDMLLAVF EDAVKACTDE SLAVEERIEA CLPLYTNMIA LHQLLERYEA AMELCKSLLE SCPINCQLLE ALVALYLQTN QHDKARAVWL TAFEKNPQNA EVFYHMCKFF ILQNRGDNLL PFLRKFIASF FKPGFEKYNN LDLFRYLLNI PGPIDIPSRL CKGNFDDDMF NHQVPYLWLI YCLCHPLQSS IKETVEAYEA ALGVAMRCDI VQKIWMDYLV FANNRAAGSR NKVQEFKFFT DLVNRCLVTV PARYPIPFSS ADYWSNYEFH NRVIFFYLSC VPKTQHSKTL ERFCSVMPAN SGLALRLLQH EWEESNVQIL KLQAKMFTYN IPTCLATWKI AIAAEIVLKG QREVHRLYQR ALQKLPLCAS LWKDQLLFEA SEGGKTDNLR KLVSKCQEIG VSLNELLNLN SNKTESKNH
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