About Katanin-interacting protein
Katanin-interacting protein (KATNIP) is a protein
from Homo sapiens identified by UniProt accession
O60303, 1618 residues long.
MolForge cross-references it against 0 known binders and
76 disease associations.
Target properties
| Protein name | Katanin-interacting protein |
|---|
| UniProt accession | O60303 |
|---|
| Gene | KATNIP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1618 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (76)
Diseases linked to this target (Open Targets).
- Joubert syndrome · score 0.62
- hypothyroidism · score 0.40
- ciliopathy · score 0.37
- Hashimoto's thyroiditis · score 0.36
- autoimmune disease · score 0.29
- thyroid disease · score 0.26
- eosinophil count · score 0.17
- mean corpuscular volume · score 0.12
- Joubert syndrome 1 · score 0.12
- mean reticulocyte volume · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60303-F1 | alphafold | PREDICTED | 58.42 | — |
Amino-acid sequence (1618 residues)
MDGQTLRKAE RSWSCSREKK EGYAKDMVTD FDEKHDEYLI LLQQRNRILK HLKSKDPVQL RLEHLEQGFS VYVNGANSEL KSSPRKAIHS DFSRSASHTE GTHDYGRRTL FREAEEALRR SSRTAPSKVQ RRGWHQKSVQ IRTEAGPRLH IEPPVDYSDD FELCGDVTLQ ANNTSEDRPQ ELRRSLELSV NLQRKQKDCS SDEYDSIEED ILSEPEPEDP ALVGHPRHDR PPSSGDWTQK DVHGEQETEG RSSPGPDTLV VLEFNPASKS HKRERNLSAK RKDNAEVFVP TKPEPNLTPQ APAVFPDQER MCSRPGSRRE RPLSATRKTL CEAEYPEEDA SAVLQAIQVE NAALQRALLS RKAEQPASPL QDAEGPPAKP WTSLLEEKEE TLELLPITTA TTTQEPAGAA GGARAINQAM DRIGLLGSRQ QQKLLKVLQA VESDSAHLGR VVSPTKEQVS DTEDKQRMRA DEIKDAIYVT MEILSNWGNS WWVGLTEVEF FDLNDTKLYV SPHDVDIRNT ATPGELGRLV NRNLAGKKDS SPWTCPFHPP LQLFFVIRNT RQLGDFHLAK IKVRNYWTAD GDLDIGAKNV KLYVNRNLIF NGKLDKGDRE APADHSILVD QKNEKSEQLE EAMNAHSEES KGTHEMAGAS GDKELGLGCS PPAETLADAK LSSQGNVSGK RKNSTNCRKD SLSQLEEYLR LSAVPTSMGD MPSAPATSPP VKCPPVHEEP SLIQQLENLM GRKICEPPGK TPSWLQPSPT GKDRKQGGRK PKPLWLSPEK PLAWKGRLPS DDVIGEGPGE TEARDKGLRH EPGWGTSRSV NTKERPQRAT TKVHSDDSDI FNQPPNRERP ASGRRGSRKD AGSSSHGDDQ PASREDTWSS RTPSRSRWRS EQEHTLHESW SSLSAFDRSH RGRISNTELP GDILDELLQQ KSSRHSDLPP SKKGEQPGLS RGQDGYSGET DAGGDFKIPV LPYGQRLVID IKSTWGDRHY VGLNGIEIFS SKGEPVQISN IKADPPDINI LPAYGKDPRV VTNLIDGVNR TQDDMHVWLA PFTRGRSHSI TIDFTHPCHV ALIRIWNYNK SRIHSFRGVK DITMLLDTQC IFEGEIAKAS GTLAGAPEHF GDTILFTTDD DILEAIFYSD EMFDLDVGSL DSLQDEEAMR RPSTADGEGD ERPFTQAGLG ADERIPELEL PSSSPVPQVT TPEPGIYHGI CLQLNFTASW GDLHYLGLTG LEVVGKEGQA LPIHLHQISA SPRDLNELPE YSDDSRALDK LIDGTNITME DEHMWLIPFS PGLDHVVTIR LDRAESIAGL RFWNYNKSPE DTYRGAKIVH VSLDGLCVSP PEGFLIRKGP GNCHFDFAQE ILFVDYLRAQ LLPQPARRLD MRSLECASMD YEAPLMPCGF IFQFQLLTSW GDPYYIGLTG LELYDERGEK IPLSENNIAA FPDSVNSLEG VGGDVRTPDK LIDQVNDTSD GRHMWLAPIL PGLVNRVYVI FDLPTTVSMI KLWNYAKTPH RGVKEFGLLV DDLLVYNGIL AMVSHLVGGI LPTCEPTVPY HTILFTEDRD IRHQEKHTTI SNQAEDQDVQ MMNENQIITN AKRKQSVVDP ALRPKTCISE KETRRRRC
Explore Katanin-interacting protein with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets