Zinc finger protein 500 (ZNF500)

About Zinc finger protein 500

Zinc finger protein 500 (ZNF500) is a protein from Homo sapiens identified by UniProt accession O60304, 480 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Zinc finger protein 500
UniProt accession	O60304
Gene	ZNF500
Organism	Homo sapiens
Length	480 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

body height · score 0.22
ferritin measurement · score 0.12
lean body mass · score 0.08
fat body mass · score 0.07
whole body water mass · score 0.06
pulse pressure measurement · score 0.03
systolic blood pressure · score 0.02
triple-negative breast cancer · score 0.01
neoplasm · score 0.00
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60304-F1	alphafold	PREDICTED	60.39	—

Amino-acid sequence (480 residues)

MATVPGLQPL PTLEQDLEQE EILIVKVEED FCLEEEPSVE TEDPSPETFR QLFRLFCYQE VAGPREALSR LWELCCRWLR PELRTKEQIL ELLVLEQFLT VLPGEIQARV REQQPESGEE AVVLVEGLQR KPRKHRQRGS ELLSDDEVPL GIGGQFLKHQ AEAQPEDLSL EEEARFSSQQ PPAQLSHRPQ RGPLLWPERG PPAPRHQEMA SASPFLSAWS QVPVNLEDVA VYLSGEEPRC MDPAQRDAPL ENEGPGIQLE DGGDGREDAP LRMEWYRVLS ARCQGPGHPL PGQRPAPVRG LVRPDQPRGG PPPGRRASHG ADKPYTCPEC GKGFSKTSHL TKHQRTHTGE RPYKCLVCGK GFSDRSNFST HQRVHTGEKP YPCPECGKRF SQSSSLVIHR RTHSGERPYA CTQCGKRFNN SSHFSAHRRT HTGEKPYTCP ACGRGFRRGT DLHKHQRTHM GAGSLPTLQP VAPGGPGAKA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards