Protein ENTREP2 (ENTREP2)

About Protein ENTREP2

Protein ENTREP2 (ENTREP2) is a protein from Homo sapiens identified by UniProt accession O60320, 539 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Protein ENTREP2
UniProt accession	O60320
Gene	ENTREP2
Organism	Homo sapiens
Length	539 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

lung disease, immunodeficiency, and chromosome breakage syndrome; · score 0.44
unipolar depression · score 0.33
bone density · score 0.30
urate measurement · score 0.30
skin pigmentation measurement · score 0.24
triglyceride measurement · score 0.16
heel bone mineral density · score 0.08
blood protein measurement · score 0.04
glioblastoma multiforme · score 0.03
hair colour measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60320-F1	alphafold	PREDICTED	59.01	—

Amino-acid sequence (539 residues)

MPPAGGPRAP RPAALPRSLS RLRECPGRSR IVLALGATQM ALGCLIVAVS FAALALTTSA RVRHSCPFWA GFSVLLSGLI GVVSWKRPLS LVITFFMLLS AVCVMLNLAG SILSCQNAQL VNSLEGCQLI KFDSVEVCVC CELQHQSSGC SNLGETLKLN PLQENCNAVR LTLKDLLFSV CALNVLSTIV CALATAMCCM QMVSSDVLQM FLPQRSHPAN PTCVTPHGTV LHQTLDFDEF IPPLPPPPYY PPEYTCTPST EAQRGLHLDF APSPFGTLYD VAINSPGLLY PAELPPPYEA VVGQPPASQV TSIGQQVAES SSGDPNTSAG FSTPVPADST SLLVSEGTAT PGSSPSPDGP VGAPAPSEPA LPPGHVSPED PGMGSQVQPG PGRVSRSTSD PTLCTSSMAG DASSHRPSCS QDLEAGLSEA VPGSASMSRS ATAACRAQLS PAGDPDTWKT DQRPTPEPFP ATSKERPRSL VDSKAYADAR VLVAKFLEHS HCALPTEAQH MVGAMRLAVT NEERLEEEAV FGADVLDQV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards