Nuclear protein 1 (NUPR1)

About Nuclear protein 1

Nuclear protein 1 (NUPR1) is a protein from Homo sapiens identified by UniProt accession O60356, 82 residues long. MolForge cross-references it against 0 known binders and 213 disease associations.

Target properties

Protein name	Nuclear protein 1
UniProt accession	O60356
Gene	NUPR1
Organism	Homo sapiens
Length	82 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (213)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.12
hepatocellular carcinoma · score 0.11
type 1 diabetes mellitus · score 0.11
serum metabolite measurement · score 0.10
urinary metabolite measurement · score 0.09
alcohol consumption measurement · score 0.09
HbA1c measurement · score 0.08
cortical thickness · score 0.08
oral squamous cell carcinoma · score 0.08
obesity · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60356-F1	alphafold	PREDICTED	70.94	—

Amino-acid sequence (82 residues)

MATFPPATSA PQQPPGPEDE DSSLDESDLY SLAHSYLGGG GRKGRTKREA AANTNRPSPG GHERKLVTKL QNSERKKRGA RR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards