About Olfactory receptor 10H2
Olfactory receptor 10H2 (OR10H2) is a protein
from Homo sapiens identified by UniProt accession
O60403, 315 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 10H2 |
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| UniProt accession | O60403 |
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| Gene | OR10H2 |
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| Organism | Homo sapiens |
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| Length | 315 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- chronic lymphocytic leukemia · score 0.18
- breast adenocarcinoma · score 0.18
- glioma · score 0.11
- low density lipoprotein cholesterol measurement · score 0.03
- total cholesterol measurement · score 0.02
- diabetic nephropathy · score 0.01
- congenital heart disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60403-F1 | alphafold | PREDICTED | 88.03 | — |
Amino-acid sequence (315 residues)
MLGLNHTSMS EFILVGFSAF PHLQLMLFLL FLLMYLFTLL GNLLIMATVW SERSLHTPMY LFLCVLSVSE ILYTVAIIPR MLADLLSTQR SIAFLACASQ MFFSFSFGFT HSFLLTVMGY DRYVAICHPL RYNVLMSPRG CACLVGCSWA GGSVMGMVVT SAIFQLTFCG SHEIQHFLCH VPPLLKLACG NNVPAVALGV GLVCIMALLG CFLLILLSYA FIVADILKIP SAEGRNKAFS TCASHLIVVI VHYGFASVIY LKPKGPHSQE GDTLMATTYA VLTPFLSPII FSLRNKELKV AMKRTFLSTL YSSGT
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