About Olfactory receptor 10H3
Olfactory receptor 10H3 (OR10H3) is a protein
from Homo sapiens identified by UniProt accession
O60404, 316 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 10H3 |
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| UniProt accession | O60404 |
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| Gene | OR10H3 |
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| Organism | Homo sapiens |
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| Length | 316 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (9)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- low grade glioma · score 0.18
- prostate adenocarcinoma · score 0.18
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- genetic disorder · score 0.12
- total cholesterol measurement · score 0.02
- glioma · score 0.02
- carcinoma of liver and intrahepatic biliary tract · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60404-F1 | alphafold | PREDICTED | 86.82 | — |
Amino-acid sequence (316 residues)
MPGQNYRTIS EFILSGFSAF PQQLLPVLFL LYLLMFLFTL LGNLLIMATV WIERRLHTPM YLFLCALSIS EILFTVAITP RMLADLLFTH RSITFVACAI QMFFSFMFGF THSFLLMVMG YDHYVTICHP LHYNMLMSPR GCAHLVAWTW AGGSVMGMMV TMMVFHLTFC GSNVIHHFLC HVLSLLKLAC GSKTSSVIMG VMLVCVTALI GCLFLIILSF VFIVAAILRI PSAEGRHKTF STCVSHLTVV VMHYSFASLI YLKPKGLHSM YSDALMATTY TVFTPFLSPI IFSLRNKELK NAINKNFCRR FCPLSS
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