About Olfactory receptor 1I1
Olfactory receptor 1I1 (OR1I1) is a protein
from Homo sapiens identified by UniProt accession
O60431, 355 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 1I1 |
|---|
| UniProt accession | O60431 |
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| Gene | OR1I1 |
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| Organism | Homo sapiens |
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| Length | 355 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- clear cell renal carcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- breast carcinoma · score 0.04
- pancreatic adenocarcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60431-F1 | alphafold | PREDICTED | 83.38 | — |
Amino-acid sequence (355 residues)
MEPEKQTEIS EFFLQGLSEK PEHQTLLFTM FLSTYLVTII GNALIILAII TDSHLHTPMY FFLFNLSLVD TLLSSTTVPK MLANIQAQSR AIPFVGCLTQ MYAFHLFGTM DSFLLAVMAI DRFVAIVHPQ RYLVLMCSPV CGLLLGASWM ITNLQSLIHT CLMAQLTFCA GSEISHFFCD LMPLLKLSGS DTHTNELVIF AFGIVVGTSP FSCILLSYIR IFWTVFKIPS TRGKWKAFST CGLHLTVVSL SYGTIFAVYL QPTSPSSSQK DKAAALMCGV FIPMLNPFIY SIRNKDMKAA LGKLIGKVAV PCPRPEQLLD VYHVPGSLLA ARDTEMHPIP YPGGVQSLAG NRDME
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