Beta-1,4-galactosyltransferase 4 (B4GALT4)

About Beta-1,4-galactosyltransferase 4

Beta-1,4-galactosyltransferase 4 (B4GALT4) is a protein from Homo sapiens identified by UniProt accession O60513, 344 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Beta-1,4-galactosyltransferase 4
UniProt accession	O60513
Gene	B4GALT4
Organism	Homo sapiens
Length	344 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

Osteoporosis · score 0.01
hepatocellular carcinoma · score 0.01
prostate adenocarcinoma · score 0.01
neoplasm · score 0.01
pancreatic carcinoma · score 0.00
psoriasis · score 0.00
cancer · score 0.00
breast cancer · score 0.00
nonpapillary renal cell carcinoma · score 0.00
chronic rhinosinusitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60513-F1	alphafold	PREDICTED	90.34	—

Amino-acid sequence (344 residues)

MGFNLTFHLS YKFRLLLLLT LCLTVVGWAT SNYFVGAIQE IPKAKEFMAN FHKTLILGKG KTLTNEASTK KVELDNCPSV SPYLRGQSKL IFKPDLTLEE VQAENPKVSR GRYRPQECKA LQRVAILVPH RNREKHLMYL LEHLHPFLQR QQLDYGIYVI HQAEGKKFNR AKLLNVGYLE ALKEENWDCF IFHDVDLVPE NDFNLYKCEE HPKHLVVGRN STGYRLRYSG YFGGVTALSR EQFFKVNGFS NNYWGWGGED DDLRLRVELQ RMKISRPLPE VGKYTMVFHT RDKGNEVNAE RMKLLHQVSR VWRTDGLSSC SYKLVSVEHN PLYINITVDF WFGA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards