Persephin (PSPN)

About Persephin

Persephin (PSPN) is a protein from Homo sapiens identified by UniProt accession O60542, 156 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Persephin
UniProt accession	O60542
Gene	PSPN
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

atrial fibrillation · score 0.04
oral squamous cell carcinoma · score 0.02
neoplasm · score 0.02
infection · score 0.01
infect · score 0.01
Parkinson disease · score 0.01
adenocarcinoma · score 0.01
bacteriemia · score 0.01
McLeod neuroacanthocytosis syndrome · score 0.01
inflammatory bowel disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60542-F1	alphafold	PREDICTED	77.99	—

Amino-acid sequence (156 residues)

MAVGKFLLGS LLLLSLQLGQ GWGPDARGVP VADGEFSSEQ VAKAGGTWLG THRPLARLRR ALSGPCQLWS LTLSVAELGL GYASEEKVIF RYCAGSCPRG ARTQHGLALA RLQGQGRAHG GPCCRPTRYT DVAFLDDRHR WQRLPQLSAA ACGCGG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards