About Lipid transferase CIDEA
Lipid transferase CIDEA (CIDEA) is a protein
from Homo sapiens identified by UniProt accession
O60543, 219 residues long.
MolForge cross-references it against 0 known binders and
128 disease associations.
Target properties
| Protein name | Lipid transferase CIDEA |
|---|
| UniProt accession | O60543 |
|---|
| Gene | CIDEA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 219 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (128)
Diseases linked to this target (Open Targets).
- attention deficit hyperactivity disorder · score 0.12
- glioblastoma multiforme · score 0.10
- esophageal cancer · score 0.10
- esophageal squamous cell carcinoma · score 0.08
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.05
- Fuchs endothelial corneal dystrophy · score 0.05
- macular corneal dystrophy · score 0.05
- granular corneal dystrophy type I · score 0.05
- central nervous system cancer · score 0.04
- Barrett's esophagus · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60543-F1 | alphafold | PREDICTED | 75.25 | — |
Amino-acid sequence (219 residues)
MEAARDYAGA LIRPLTFMGS QTKRVLFTPL MHPARPFRVS NHDRSSRRGV MASSLQELIS KTLDALVIAT GLVTLVLEED GTVVDTEEFF QTLGDNTHFM ILEKGQKWMP GSQHVPTCSP PKRSGIARVT FDLYRLNPKD FIGCLNVKAT MYEMYSVSYD IRCTGLKGLL RSLLRFLSYS AQVTGQFLIY LGTYMLRVLD DKEERPSLRS QAKGRFTCG
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