About Eukaryotic translation initiation factor 4E type 2
Eukaryotic translation initiation factor 4E type 2 (EIF4E2) is a protein
from Homo sapiens identified by UniProt accession
O60573, 245 residues long.
MolForge cross-references it against 0 known binders and
57 disease associations.
Target properties
| Protein name | Eukaryotic translation initiation factor 4E type 2 |
|---|
| UniProt accession | O60573 |
|---|
| Gene | EIF4E2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 245 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (57)
Diseases linked to this target (Open Targets).
- body height · score 0.34
- platelet count · score 0.32
- vital capacity · score 0.32
- lymphocyte count · score 0.31
- mean corpuscular volume · score 0.27
- mathematical ability · score 0.25
- diet measurement · score 0.23
- blood protein measurement · score 0.23
- platelet component distribution width · score 0.23
- age at first facial hair · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60573-F1 | alphafold | PREDICTED | 80.35 | — |
Amino-acid sequence (245 residues)
MNNKFDALKD DDSGDHDQNE ENSTQKDGEK EKTERDKNQS SSKRKAVVPG PAEHPLQYNY TFWYSRRTPG RPTSSQSYEQ NIKQIGTFAS VEQFWRFYSH MVRPGDLTGH SDFHLFKEGI KPMWEDDANK NGGKWIIRLR KGLASRCWEN LILAMLGEQF MVGEEICGAV VSVRFQEDII SIWNKTASDQ ATTARIRDTL RRVLNLPPNT IMEYKTHTDS IKMPGRLGPQ RLLFQNLWKP RLNVP
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