Selenoprotein F (SELENOF)

Homo sapiens — UniProt O60613

Gene: SELENOFHomo sapiensSwissProt reviewed

About Selenoprotein F

Selenoprotein F (SELENOF) is a protein from Homo sapiens identified by UniProt accession O60613, 165 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.

Target properties

Protein nameSelenoprotein F
UniProt accessionO60613
GeneSELENOF
OrganismHomo sapiens
Length165 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (125)

Diseases linked to this target (Open Targets).

  • mathematical ability · score 0.21
  • early-onset non-syndromic cataract · score 0.07
  • Cataract-microcornea syndrome · score 0.07
  • Total congenital cataract · score 0.07
  • Anterior polar cataract · score 0.06
  • Cataract with Y-shaped suture opacities · score 0.06
  • Posterior polar cataract · score 0.06
  • cataract · score 0.06
  • hereditary hyperferritinemia with congenital cataracts · score 0.06
  • isolated ectopia lentis · score 0.06

3D Structure

Predicted structure for O60613 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (165 residues)

MVAMAAGPSG CLVPAFGLRL LLATVLQAVS AFGAEFSSEA CRELGFSSNL LCSSCDLLGQ FNLLQLDPDC RGCCQEEAQF ETKKLYAGAI LEVCGUKLGR FPQVQAFVRS DKPKLFRGLQ IKYVRGSDPV LKLLDDNGNI AEELSILKWN TDSVEEFLSE KLERI

Explore Selenoprotein F with MolForge

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Quick facts

UniProtO60613
GeneSELENOF
OrganismHomo sapiens
Length165
Binders0
Diseases125
View on UniProt