Monocarboxylate transporter 2 (SLC16A7)

About Monocarboxylate transporter 2

Monocarboxylate transporter 2 (SLC16A7) is a protein from Homo sapiens identified by UniProt accession O60669, 478 residues long. MolForge cross-references it against 0 known binders and 136 disease associations.

Target properties

Protein name	Monocarboxylate transporter 2
UniProt accession	O60669
Gene	SLC16A7
Organism	Homo sapiens
Length	478 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (136)

Diseases linked to this target (Open Targets).

body height · score 0.43
BMI-adjusted waist-hip ratio · score 0.36
self reported educational attainment · score 0.34
mean corpuscular volume · score 0.33
BMI-adjusted hip circumference · score 0.30
diet measurement · score 0.29
mathematical ability · score 0.28
neurodegenerative disease · score 0.28
multiple sclerosis · score 0.28
lysosomal storage disease · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60669-F1	alphafold	PREDICTED	84.46	—

Amino-acid sequence (478 residues)

MPPMPSAPPV HPPPDGGWGW IVVGAAFISI GFSYAFPKAV TVFFKEIQQI FHTTYSEIAW ISSIMLAVMY AGGPVSSVLV NKYGSRPVVI AGGLLCCLGM VLASFSSSVV QLYLTMGFIT GLGLAFNLQP ALTIIGKYFY RKRPMANGLA MAGSPVFLSS LAPFNQYLFN TFGWKGSFLI LGSLLLNACV AGSLMRPLGP NQTTSKSKNK TGKTEDDSSP KKIKTKKSTW EKVNKYLDFS LFKHRGFLIY LSGNVIMFLG FFAPIIFLAP YAKDQGIDEY SAAFLLSVMA FVDMFARPSV GLIANSKYIR PRIQYFFSFA IMFNGVCHLL CPLAQDYTSL VLYAVFFGLG FGSVSSVLFE TLMDLVGAPR FSSAVGLVTI VECGPVLLGP PLAGKLVDLT GEYKYMYMSC GAIVVAASVW LLIGNAINYR LLAKERKEEN ARQKTRESEP LSKSKHSEDV NVKVSNAQSV TSERETNI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards