Transcription factor MafK (MAFK)

About Transcription factor MafK

Transcription factor MafK (MAFK) is a protein from Homo sapiens identified by UniProt accession O60675, 156 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.

Target properties

Protein name	Transcription factor MafK
UniProt accession	O60675
Gene	MAFK
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (77)

Diseases linked to this target (Open Targets).

body height · score 0.31
serum gamma-glutamyl transferase measurement · score 0.29
appendicular lean mass · score 0.27
blood protein measurement · score 0.18
fat body mass · score 0.12
platelet count · score 0.09
monocyte count · score 0.07
lean body mass · score 0.07
Salmonella Infections · score 0.05
ulcerative colitis · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O60675-F1	alphafold	PREDICTED	83.24	—

Amino-acid sequence (156 residues)

MTTNPKPNKA LKVKKEAGEN APVLSDDELV SMSVRELNQH LRGLTKEEVT RLKQRRRTLK NRGYAASCRI KRVTQKEELE RQRVELQQEV EKLARENSSM RLELDALRSK YEALQTFART VARGPVAPSK VATTSVITIV KSTELSSTSV PFSAAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards