About Musculin
Musculin (MSC) is a protein
from Homo sapiens identified by UniProt accession
O60682, 206 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Musculin |
|---|
| UniProt accession | O60682 |
|---|
| Gene | MSC |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- body height · score 0.36
- cutaneous melanoma · score 0.35
- cystatin C measurement · score 0.32
- adolescent idiopathic scoliosis · score 0.29
- nevus count · score 0.28
- creatinine measurement · score 0.26
- lymphocyte count · score 0.19
- insulin resistance · score 0.15
- lymphocyte percentage of leukocytes · score 0.11
- systemic lupus erythematosus · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60682-F1 | alphafold | PREDICTED | 64.42 | — |
Amino-acid sequence (206 residues)
MSTGSVSDPE EMELRGLQRE YPVPASKRPP LRGVERSYAS PSDNSSAEEE DPDGEEERCA LGTAGSAEGC KRKRPRVAGG GGAGGSAGGG GKKPLPAKGS AAECKQSQRN AANARERARM RVLSKAFSRL KTSLPWVPPD TKLSKLDTLR LASSYIAHLR QLLQEDRYEN GYVHPVNLTW PFVVSGRPDS DTKEVSAANR LCGTTA
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