About Eukaryotic translation initiation factor 1b
Eukaryotic translation initiation factor 1b (EIF1B) is a protein
from Homo sapiens identified by UniProt accession
O60739, 113 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Eukaryotic translation initiation factor 1b |
|---|
| UniProt accession | O60739 |
|---|
| Gene | EIF1B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 113 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.16
- body weights and measures · score 0.15
- metabolite measurement · score 0.08
- eosinophil percentage of leukocytes · score 0.07
- attention deficit hyperactivity disorder · score 0.06
- deafness · score 0.05
- Tourette syndrome · score 0.05
- schizophrenia 15 · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
- X-linked dominant intellectual disability - epilepsy syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60739-F1 | alphafold | PREDICTED | 79.77 | — |
Amino-acid sequence (113 residues)
MSTIQNLQSF DPFADATKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI ADDYDKKKLV KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLLEV GIVKEEQLKV HGF
Explore Eukaryotic translation initiation factor 1b with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets