About Cytohesin-interacting protein
Cytohesin-interacting protein (CYTIP) is a protein
from Homo sapiens identified by UniProt accession
O60759, 359 residues long.
MolForge cross-references it against 0 known binders and
109 disease associations.
Target properties
| Protein name | Cytohesin-interacting protein |
|---|
| UniProt accession | O60759 |
|---|
| Gene | CYTIP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 359 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (109)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.37
- urate measurement · score 0.32
- vitamin B6 measurement · score 0.32
- neurodegenerative disease · score 0.26
- bilirubin measurement · score 0.25
- birth weight · score 0.19
- inflammatory bowel disease · score 0.16
- reticulocyte count · score 0.11
- BMI-adjusted waist-hip ratio · score 0.08
- HbA1c measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60759-F1 | alphafold | PREDICTED | 62.63 | — |
Amino-acid sequence (359 residues)
MSLQRLLQHS SNGNLADFCA GPAYSSYSTL TGSLTMDDNR RIQMLADTVA TLPRGRKQLA LTRSSSLSDF SWSQRKLVTV EKQDNETFGF EIQSYRPQNQ NACSSEMFTL ICKIQEDSPA HCAGLQAGDV LANINGVSTE GFTYKQVVDL IRSSGNLLTI ETLNGTMILK RTELEAKLQV LKQTLKQKWV EYRSLQLQEH RLLHGDAANC PSLENMDLDE LSLFGPLPGP GPALVDRNRL SSESSCKSWL SSMTMDSEDG YQTCVSEDSS RGAFSRQTST DDECFIPKEG DDFLRRSSSR RNRSISNTSS GSMSPLWEGN LSSMFGTLPR KSRKGSVRKQ LLKFIPGLHR AVEEEESRF
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