About Zymogen granule membrane protein 16
Zymogen granule membrane protein 16 (ZG16) is a protein
from Homo sapiens identified by UniProt accession
O60844, 167 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Zymogen granule membrane protein 16 |
|---|
| UniProt accession | O60844 |
|---|
| Gene | ZG16 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 167 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.09
- Barrett's esophagus · score 0.08
- colorectal cancer · score 0.06
- colorectal adenocarcinoma · score 0.05
- hepatocellular carcinoma · score 0.05
- X-linked agammaglobulinemia · score 0.04
- isolated agammaglobulinemia · score 0.04
- immunodeficiency 35 · score 0.04
- mannose-binding lectin deficiency · score 0.04
- Immunodeficiency by defective expression of HLA class 2 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60844-F1 | alphafold | PREDICTED | 91.03 | — |
Amino-acid sequence (167 residues)
MLTVALLALL CASASGNAIQ ARSSSYSGEY GGGGGKRFSH SGNQLDGPIT ALRVRVNTYY IVGLQVRYGK VWSDYVGGRN GDLEEIFLHP GESVIQVSGK YKWYLKKLVF VTDKGRYLSF GKDSGTSFNA VPLHPNTVLR FISGRSGSLI DAIGLHWDVY PSSCSRC
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