About F-box-like/WD repeat-containing protein TBL1X
F-box-like/WD repeat-containing protein TBL1X (TBL1X) is a protein
from Homo sapiens identified by UniProt accession
O60907, 577 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | F-box-like/WD repeat-containing protein TBL1X |
|---|
| UniProt accession | O60907 |
|---|
| Gene | TBL1X |
|---|
| Organism | Homo sapiens |
|---|
| Length | 577 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- hypothyroidism, congenital, nongoitrous · score 0.46
- viral disease · score 0.37
- X-linked recessive ocular albinism · score 0.33
- hemoglobin A1 measurement · score 0.32
- breast adenocarcinoma · score 0.27
- head and neck squamous cell carcinoma · score 0.25
- endometrial cancer · score 0.22
- genetic disorder · score 0.19
- ovarian cancer · score 0.18
- nystagmus 6, congenital, X-linked · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60907-F1 | alphafold | PREDICTED | 82.27 | — |
Amino-acid sequence (577 residues)
MTELAGASSS CCHRPAGRGA MQSVLHHFQR LRGREGGSHF INTSSPRGEA KMSITSDEVN FLVYRYLQES GFSHSAFTFG IESHISQSNI NGTLVPPAAL ISILQKGLQY VEAEISINED GTVFDGRPIE SLSLIDAVMP DVVQTRQQAF REKLAQQQAS AAAAAAAATA AATAATTTSA GVSHQNPSKN REATVNGEEN RAHSVNNHAK PMEIDGEVEI PSSKATVLRG HESEVFICAW NPVSDLLASG SGDSTARIWN LNENSNGGST QLVLRHCIRE GGHDVPSNKD VTSLDWNTNG TLLATGSYDG FARIWTEDGN LASTLGQHKG PIFALKWNRK GNYILSAGVD KTTIIWDAHT GEAKQQFPFH SAPALDVDWQ NNTTFASCST DMCIHVCRLG CDRPVKTFQG HTNEVNAIKW DPSGMLLASC SDDMTLKIWS MKQEVCIHDL QAHNKEIYTI KWSPTGPATS NPNSNIMLAS ASFDSTVRLW DIERGVCTHT LTKHQEPVYS VAFSPDGKYL ASGSFDKCVH IWNTQSGNLV HSYRGTGGIF EVCWNARGDK VGASASDGSV CVLDLRK
Explore F-box-like/WD repeat-containing protein TBL1X with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets