About Nucleolar protein 3
Nucleolar protein 3 (NOL3) is a protein
from Homo sapiens identified by UniProt accession
O60936, 208 residues long.
MolForge cross-references it against 0 known binders and
83 disease associations.
Target properties
| Protein name | Nucleolar protein 3 |
|---|
| UniProt accession | O60936 |
|---|
| Gene | NOL3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (83)
Diseases linked to this target (Open Targets).
- Familial cortical myoclonus · score 0.65
- neurodegenerative disease · score 0.25
- myeloproliferative disorder · score 0.07
- chronic myeloproliferative disorder · score 0.07
- mean corpuscular volume · score 0.07
- mean corpuscular hemoglobin concentration · score 0.04
- neuronal ceroid lipofuscinosis 1 · score 0.04
- sitting height measurement · score 0.04
- kidney disease · score 0.04
- neutropenia, severe congenital, 9, autosomal dominant · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60936-F1 | alphafold | PREDICTED | 71.63 | — |
Amino-acid sequence (208 residues)
MGNAQERPSE TIDRERKRLV ETLQADSGLL LDALLARGVL TGPEYEALDA LPDAERRVRR LLLLVQGKGE AACQELLRCA QRTAGAPDPA WDWQHVGPGY RDRSYDPPCP GHWTPEAPGS GTTCPGLPRA SDPDEAGGPE GSEAVQSGTP EEPEPELEAE ASKEAEPEPE PEPELEPEAE AEPEPELEPE PDPEPEPDFE ERDESEDS
Explore Nucleolar protein 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets