About Keratocan
Keratocan (KERA) is a protein
from Homo sapiens identified by UniProt accession
O60938, 352 residues long.
MolForge cross-references it against 0 known binders and
103 disease associations.
Target properties
| Protein name | Keratocan |
|---|
| UniProt accession | O60938 |
|---|
| Gene | KERA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 352 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (103)
Diseases linked to this target (Open Targets).
- cornea plana 2 · score 0.71
- cornea plana · score 0.37
- congenital cornea plana · score 0.37
- viral load · score 0.30
- cutaneous melanoma · score 0.26
- lung adenocarcinoma · score 0.25
- protein measurement · score 0.23
- body fat percentage · score 0.18
- breast adenocarcinoma · score 0.11
- gastric adenocarcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O60938-F1 | alphafold | PREDICTED | 87.56 | — |
Amino-acid sequence (352 residues)
MAGTICFIMW VLFITDTVWS RSVRQVYEVH DSDDWTIHDF ECPMECFCPP SFPTALYCEN RGLKEIPAIP SRIWYLYLQN NLIETIPEKP FENATQLRWI NLNKNKITNY GIEKGALSQL KKLLFLFLED NELEEVPSPL PRSLEQLQLA RNKVSRIPQG TFSNLENLTL LDLQNNKLVD NAFQRDTFKG LKNLMQLNMA KNALRNMPPR LPANTMQLFL DNNSIEGIPE NYFNVIPKVA FLRLNHNKLS DEGLPSRGFD VSSILDLQLS HNQLTKVPRI SAHLQHLHLD HNKIKSVNVS VICPSPSMLP AERDSFSYGP HLRYLRLDGN EIKPPIPMAL MTCFRLLQAV II
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