About Leukocyte immunoglobulin-like receptor subfamily A member 1
Leukocyte immunoglobulin-like receptor subfamily A member 1 (LILRA1) is a protein
from Homo sapiens identified by UniProt accession
O75019, 489 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 1 |
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| UniProt accession | O75019 |
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| Gene | LILRA1 |
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| Organism | Homo sapiens |
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| Length | 489 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.15
- leukocyte immunoglobulin-like receptor subfamily B member 1 measurement · score 0.10
- blood protein measurement · score 0.08
- Crohn's disease · score 0.02
- osteosarcoma · score 0.02
- ulcerative colitis · score 0.02
- myeloid sarcoma · score 0.01
- acute lymphoblastic leukemia · score 0.01
- tuberculosis · score 0.01
- multiple sclerosis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75019-F1 | alphafold | PREDICTED | 83.91 | — |
Amino-acid sequence (489 residues)
MTPIVTVLIC LRLSLGPRTH VQAGTLPKPT LWAEPGSVIT QGSPVTLWCQ GILETQEYRL YREKKTAPWI TRIPQEIVKK GQFPIPSITW EHTGRYRCFY GSHTAGWSEP SDPLELVVTG AYIKPTLSAL PSPVVTSGGN VTLHCVSQVA FGSFILCKEG EDEHPQCLNS QPRTHGWSRA IFSVGPVSPS RRWSYRCYAY DSNSPHVWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPGE SLTLQCVSDV SYDRFVLYKE GERDFLQLPG PQPQAGLSQA NFTLGPVSRS YGGQYRCSGA YNLSSEWSAP SDPLDILIAG QFRGRPFISV HPGPTVASGE NVTLLCQSWG PFHTFLLTKA GAADAPLRLR SIHEYPKYQA EFPMSPVTSA HSGTYRCYGS LSSNPYLLSH PSDSLELMVS GAAETLSPPQ NKSDSKAGAA NTLSPSQNKT ASHPQDYTVE NLIRMGIAGL VLVVLGILLF EAQHSQRSL
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