Microfibrillar-associated protein 3-like (MFAP3L)

About Microfibrillar-associated protein 3-like

Microfibrillar-associated protein 3-like (MFAP3L) is a protein from Homo sapiens identified by UniProt accession O75121, 409 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	Microfibrillar-associated protein 3-like
UniProt accession	O75121
Gene	MFAP3L
Organism	Homo sapiens
Length	409 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.45
calcium measurement · score 0.33
diet measurement · score 0.30
thyroxine measurement · score 0.29
mathematical ability · score 0.28
alcohol consumption measurement · score 0.19
lean body mass · score 0.16
fat body mass · score 0.16
body weight · score 0.15
atopic march · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75121-F1	alphafold	PREDICTED	61.61	—

Amino-acid sequence (409 residues)

MDRLKSHLTV CFLPSVPFLI LVSTLATAKS VTNSTLNGTN VVLGSVPVII ARTDHIIVKE GNSALINCSV YGIPDPQFKW YNSIGKLLKE EEDEKERGGG KWQMHDSGLL NITKVSFSDR GKYTCVASNI YGTVNNTVTL RVIFTSGDMG VYYMVVCLVA FTIVMVLNIT RLCMMSSHLK KTEKAINEFF RTEGAEKLQK AFEIAKRIPI ITSAKTLELA KVTQFKTMEF ARYIEELARS VPLPPLIMNC RTIMEEIMEV VGLEEQGQNF VRHTPEGQEA ADRDEVYTIP NSLKRSDSPA ADSDASSLHE QPQQIAIKVS VHPQSKKEHA DDQEGGQFEV KDVEETELSA EHSPETAEPS TDVTSTELTS EEPTPVEVPD KVLPPAYLEA TEPAVTHDKN TCIIYESHV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards