Zinc finger protein 623 (ZNF623)

About Zinc finger protein 623

Zinc finger protein 623 (ZNF623) is a protein from Homo sapiens identified by UniProt accession O75123, 536 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Zinc finger protein 623
UniProt accession	O75123
Gene	ZNF623
Organism	Homo sapiens
Length	536 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.49
platelet count · score 0.03
serum metabolite measurement · score 0.03
hepatocellular carcinoma · score 0.02
breast cancer · score 0.02
breast carcinoma · score 0.01
cancer · score 0.01
neoplasm · score 0.00
gastric carcinoma · score 0.00
metastatic melanoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75123-F1	alphafold	PREDICTED	71.12	—

Amino-acid sequence (536 residues)

MILLSFVSDS NVGTGEKKVT EAWISEDENS HRTTSDRLTV MELPSPESEE VHEPRLGELL GNPEGQSLGS SPSQDRGCKQ VTVTHWKIQT GETAQVCTKS GRNHILNSDL LLLQRELIEG EANPCDICGK TFTFNSDLVR HRISHAGEKP YTCDQCGKGF GQSSHLMEHQ RIHTGERLYV CNVCGKDFIH YSGLIEHQRV HSGEKPFKCA QCGKAFCHSS DLIRHQRVHT RERPFECKEC GKGFSQSSLL IRHQRIHTGE RPYECNECGK SFIRSSSLIR HYQIHTEVKQ YECKECGKAF RHRSDLIEHQ RIHTGERPFE CNECGKAFIR SSKLIQHQRI HTGERPYVCN ECGKRFSQTS NFTQHQRIHT GEKLYECNEC GKAFFLSSYL IRHQKIHTGE RVYECKECGK AFLQKAHLTE HQKIHSGDRP FECKDCGKAF IQSSKLLLHQ IIHTGEKPYV CSYCGKGFIQ RSNFLQHQKI HTEEKLYECS QYGRDFNSTT NVKNNQRVHQ EGLSLSKAPI HLGERSVDKG EHTGNL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards