About Zinc finger BED domain-containing protein 4
Zinc finger BED domain-containing protein 4 (ZBED4) is a protein
from Homo sapiens identified by UniProt accession
O75132, 1171 residues long.
MolForge cross-references it against 0 known binders and
45 disease associations.
Target properties
| Protein name | Zinc finger BED domain-containing protein 4 |
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| UniProt accession | O75132 |
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| Gene | ZBED4 |
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| Organism | Homo sapiens |
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| Length | 1171 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- Short stature · score 0.33
- heel bone mineral density · score 0.20
- monocyte count · score 0.18
- mean platelet volume · score 0.16
- bone quantitative ultrasound measurement · score 0.14
- bone density · score 0.14
- systolic blood pressure · score 0.14
- skin aging measurement · score 0.13
- triglyceride measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75132-F1 | alphafold | PREDICTED | 66.67 | — |
Amino-acid sequence (1171 residues)
MENNLKTCPK EDGDFVSDKI KFKIEEEDDD GIPPDSLERM DFKSEQEDMK QTDSGGERAG LGGTGCSCKP PGKYLSAESE DDYGALFSQY SSTLYDVAME AVTQSLLSSR NMSSRKKSPA WKHFFISPRD STKAICMYCV KEFSRGKNEK DLSTSCLMRH VRRAHPTVLI QENGSVSAVS SFPSPSLLLP PQPADAGDLS TILSPIKLVQ KVASKIPSPD RITEESVSVV SSEEISSDMS VSEKCGREEA LVGSSPHLPA LHYDEPAENL AEKSLPLPKS TSGSRRRSAV WKHFYLSPLD NSKAVCIHCM NEFSRGKNGK DLGTSCLIRH MWRAHRAIVL QENGGTGIPP LYSTPPTLLP SLLPPEGELS SVSSSPVKPV RESPSASSSP DRLTEDLQSH LNPGDGLMED VAAFSSSDDI GEASASSPEK QQADGLSPRL FESGAIFQQN KKVMKRLKSE VWHHFSLAPM DSLKAECRYC GCAISRGKKG DVGTSCLMRH LYRRHPEVVG SQKGFLGASL ANSPYATLAS AESSSSKLTD LPTVVTKNNQ VMFPVNSKKT SKLWNHFSIC SADSTKVVCL HCGRTISRGK KPTNLGTSCL LRHLQRFHSN VLKTEVSETA RPSSPDTRVP RGTELSGASS FDDTNEKFYD SHPVAKKITS LIAEMIALDL QPYSFVDNVG FNRLLEYLKP QYSLPAPSYF SRTAIPGMYD NVKQIIMSHL KEAESGVIHF TSGIWMSNQT REYLTLTAHW VSFESPARPR CDDHHCSALL DVSQVDCDYS GNSIQKQLEC WWEAWVTSTG LQVGITVTDN ASIGKTLNEG EHSSVQCFSH TVNLIVSEAI KSQRMVQNLL SLARKICERV HRSPKAKEKL AELQREYALP QHHLIQDVPS KWSTSFHMLE RLIEQKRAIN EMSVECNFRE LISCDQWEVM QSVCRALKPF EAASREMSTQ MSTLSQVIPM VHILNRKVEM LFEETMGIDT MLRSLKEAMV SRLSATLHDP RYVFATLLDP RYKASLFTEE EAEQYKQDLI RELELMNSTS EDVAASHRCD AGSPSKDSAA EENLWSLVAK VKKKDPREKL PEAMVLAYLE EEVLEHSCDP LTYWNLKKAS WPGLSALAVR FLGCPPSIVP SEKLFNTPTE NGSLGQSRLM MEHFEKLIFL KVNLPLIYFQ Y
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