About Xylulose kinase
Xylulose kinase (XYLB) is a protein
from Homo sapiens identified by UniProt accession
O75191, 536 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Xylulose kinase |
|---|
| UniProt accession | O75191 |
|---|
| Gene | XYLB |
|---|
| Organism | Homo sapiens |
|---|
| Length | 536 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.28
- bitter alcoholic beverage consumption measurement · score 0.23
- urinary metabolite measurement · score 0.23
- creatinine measurement · score 0.11
- appendicular lean mass · score 0.08
- electrocardiography · score 0.08
- glomerular filtration rate · score 0.07
- lean body mass · score 0.06
- alcohol consumption measurement · score 0.05
- body mass index · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75191-F1 | alphafold | PREDICTED | 95.97 | — |
Amino-acid sequence (536 residues)
MAEHAPRRCC LGWDFSTQQV KVVAVDAELN VFYEESVHFD RDLPEFGTQG GVHVHKDGLT VTSPVLMWVQ ALDIILEKMK ASGFDFSQVL ALSGAGQQHG SIYWKAGAQQ ALTSLSPDLR LHQQLQDCFS ISDCPVWMDS STTAQCRQLE AAVGGAQALS CLTGSRAYER FTGNQIAKIY QQNPEAYSHT ERISLVSSFA ASLFLGSYSP IDYSDGSGMN LLQIQDKVWS QACLGACAPH LEEKLSPPVP SCSVVGAISS YYVQRYGFPP GCKVVAFTGD NPASLAGMRL EEGDIAVSLG TSDTLFLWLQ EPMPALEGHI FCNPVDSQHY MALLCFKNGS LMREKIRNES VSRSWSDFSK ALQSTEMGNG GNLGFYFDVM EITPEIIGRH RFNTENHKVA AFPGDVEVRA LIEGQFMAKR IHAEGLGYRV MSKTKILATG GASHNREILQ VLADVFDAPV YVIDTANSAC VGSAYRAFHG LAGGTDVPFS EVVKLAPNPR LAATPSPGAS QVYEALLPQY AKLEQRILSQ TRGPPE
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