Zinc finger protein ZPR1 (ZPR1)

About Zinc finger protein ZPR1

Zinc finger protein ZPR1 (ZPR1) is a protein from Homo sapiens identified by UniProt accession O75312, 459 residues long. MolForge cross-references it against 0 known binders and 190 disease associations.

Target properties

Protein name	Zinc finger protein ZPR1
UniProt accession	O75312
Gene	ZPR1
Organism	Homo sapiens
Length	459 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (190)

Diseases linked to this target (Open Targets).

triglyceride measurement · score 0.50
growth restriction, hypoplastic kidneys, alopecia, and distinctive facies · score 0.45
high density lipoprotein cholesterol measurement · score 0.41
low density lipoprotein cholesterol measurement · score 0.41
sphingomyelin measurement · score 0.39
vitamin D measurement · score 0.37
total cholesterol measurement · score 0.37
metabolic syndrome · score 0.37
eosinophil count · score 0.35
mean corpuscular volume · score 0.35

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-O75312-F1	alphafold	PREDICTED	79.47	—

Amino-acid sequence (459 residues)

MAASGAVEPG PPGAAVAPSP APAPPPAPDH LFRPISAEDE EQQPTEIESL CMNCYCNGMT RLLLTKIPFF REIIVSSFSC EHCGWNNTEI QSAGRIQDQG VRYTLSVRAL EDMNREVVKT DSAATRIPEL DFEIPAFSQK GALTTVEGLI TRAISGLEQD QPARRANKDA TAERIDEFIV KLKELKQVAS PFTLIIDDPS GNSFVENPHA PQKDDALVIT HYNRTRQQEE MLGLQEEAPA EKPEEEDLRN EVLQFSTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS GGAVEPLGTR ITLHITDASD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD IRELVTKNPF TLGDSSNPGQ TERLQEFSQK MDQIIEGNMK AHFIMDDPAG NSYLQNVYAP EDDPEMKVER YKRTFDQNEE LGLNDMKTEG YEAGLAPQR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards