About RNA/RNP complex-1-interacting phosphatase
RNA/RNP complex-1-interacting phosphatase (DUSP11) is a protein
from Homo sapiens identified by UniProt accession
O75319, 330 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | RNA/RNP complex-1-interacting phosphatase |
|---|
| UniProt accession | O75319 |
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| Gene | DUSP11 |
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| Organism | Homo sapiens |
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| Length | 330 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (62)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.27
- glomerular filtration rate · score 0.11
- macrovascular complications of diabetes · score 0.09
- IGF-1 measurement · score 0.09
- Brugada syndrome · score 0.05
- Fuchs endothelial corneal dystrophy · score 0.04
- infect · score 0.04
- infection · score 0.04
- progressive familial heart block, type 1A · score 0.04
- snowflake vitreoretinal degeneration · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-O75319-F1 | alphafold | PREDICTED | 69.75 | — |
Amino-acid sequence (330 residues)
MSQWHHPRSG WGRRRDFSGR SSAKKKGGNH IPERWKDYLP VGQRMPGTRF IAFKVPLQKS FEKKLAPEEC FSPLDLFNKI REQNEELGLI IDLTYTQRYY KPEDLPETVP YLKIFTVGHQ VPDDETIFKF KHAVNGFLKE NKDNDKLIGV HCTHGLNRTG YLICRYLIDV EGVRPDDAIE LFNRCRGHCL ERQNYIEDLQ NGPIRKNWNS SVPRSSDFED SAHLMQPVHN KPVKQGPRYN LHQIQGHSAP RHFHTQTQSL QQSVRKFSEN PHVYQRHHLP PPGPPGEDYS HRRYSWNVKP NASRAAQDRR RWYPYNYSRL SYPACWEWTQ
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